HORDB

ID: hor001991
Uniprot ID: A8WA77
Protein name: GnRH
Gene name: GnRH
Organism: Aplysia californica (California sea hare)
Family: GnRH family
Source: animal
Expression: central nervous system (CNS), the ovotestis, and the atrial gland
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Sequence: QNYHFSNGWYAG
Length: 12
Propeptide: MACRITSATTTLFSILLLIVIAELCSAQNYHFSNGWYAGKKRSSASLLRPEALGSSSSSSSNSGLDVTDADSSRGGVSSLSGRGFGVGELRLVDSPCSIRLETLALINKLMQEEAARIQRTCVANVPSGLRELLEGAASKLESENKW
Signal peptide: MACRITSATTTLFSILLLIVIAELCSA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001991_AF2.pdb

hor001991_ESM.pdb

Mass:	163988	Formula:	C67H82N18O19
Absent amino acids:	CDEIKLMPRTV	Common amino acids:	GNY
pI:	7.53	Basic residues:	1
Polar residues:	7	Hydrophobic residues:	3
Hydrophobicity:	-118.33	Boman Index:	-1816
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	8.33
Instability Index:	2830	Extinction Coefficient cystines:	8480
Absorbance 280nm:	770.91

PubMed ID: 18178211
Title: Molecular Cloning, Expression Pattern, and Immunocytochemical Localization of a Gonadotropin-Releasing Hormone-Like Molecule in the Gastropod Mollusk, Aplysia Californica